‘We shall not be moved – El barrio no se vende’

How the Constitution Shall Not Be Construed

Catatonia in the DSM--shall we move or not?

The current issue ofSchizophreniaBulletin includes 2 opinion pieces on the nosology of catatonia and 1 on the treatment of catatonia. Fink and colleagues argue that the original concept of catatonia, introduced by Karl Kahlbaum in 1874, was inappropriately subsumed under dementia praecox and, subsequently, schizophrenia. They ask for a divorce of catatonia from schizophrenia and the recognition...

The Histone Minority Report the Variant Shall Not Be Silenced

In this issue of Cell, Meneghini et al. demonstrate that replacement of canonical histone H2A with the histone variant H2A.Z within euchromatin prevents silent chromatin proteins from migrating into regions of the chromosome that normally are transcriptionally active. Thus, this highly conserved histone variant is critical for defining chromatin domains.

What shall we call them?

When last discussed in Pediatrics in 2002, the American Academy of Pediatrics (AAP) Committee on Psychosocial Aspects of Child and Family Health statement “Coparent or Second-Parent Adoption by Same-Sex Parents”2 (reaffirmed February 2010) and the accompanying technical report written by Ellen Perrin, MD, FAAP,3 drew much attention and engendered controversy both within the AAP and outside of i...

"How then shall we live?".

This address did not originate in my neocortex, but in a deeper region of my brain, the one responsible for signaling a sense of warning. The sense I have is that a subtle, distinct change is occurring around me that is not quite right. This sense eventually grew into the perception that society, in general, and medicine, in particular, are devaluing the ideals of service and sacrifice. I did n...